FOLR1 CHO Cell Line

Catalog #

78360

$3,500 *

Size: 2 vials

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

Recombinant clonal stable CHO cell line constitutively expressing full length human folate receptor alpha (FOLR1, also known as FOLR, Genbank #NM_016725.3). Surface expression of FOLR1 was confirmed by flow cytometry.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms

FOLR1, FOLR, Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18

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Product Data Gallery

Expression of FOLR1 in FOLR1 CHO Cell Line

Product Info

Storage and Usage

Citations

Host Cell Line

CHO-K1 cells, Chinese Hamster Ovary, epithelial-like cells, adherent

Supplied As

Each vial contains 2 x 10⁶ cells in 1 ml of cell freezing medium (BPS Bioscience, #79796)

Materials Required But Not Supplied

Name	Ordering Information
Thaw Medium 3	BPS Bioscience #60186
Growth Medium 3D	BPS Bioscience #79539

UniProt #

P15328

Mycoplasma Testing

The cell line has been screened to confirm the absence of Mycoplasma species.

Background

Folate receptor alpha (FOLR1) is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that transports folate (vitamin B9) into cells. FOLR1 is overexpressed in multiple cancers such as cervical cancer, ovarian cancer, breast cancer, and brain carcinomas, and FOLR1 overexpression is associated with poor patient prognosis and increased cancer progression. The overexpression of FOLR1 in a variety of cancerous tissues makes it a valuable target for drug development. There are currently multiple drugs in clinical trials that target FOLR1.

Storage/Stability

Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Growth Media

For best results, it is highly recommended to use these validated and optimized media from BPS Bioscience. Other preparations or formulations of media may result in suboptimal performance.

Thaw Medium 3 (BPS Bioscience, #60186): F-12K medium supplemented with 10% FBS, 1% Penicillin/Streptomycin.

Growth Medium 3D (BPS Bioscience, #79539): F-12K medium supplemented with 10% FBS, 1% Penicillin/Streptomycin plus 1 mg/ml Geneticin.

Applications

Screen and validate antibodies against FOLR1 for drug discovery and research.
Screen for or characterize compounds that regulate or inhibit FOLR1 signaling in a cellular context.

Shipping Temperature

-80°C

Notes

License Disclosure
Visit bpsbioscience.com/license for the label license and other key information about this product.

Troubleshooting Guide
Visit bpsbioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected].

Warnings

Avoid freeze thaw cycles

Scientific Category

Neuroscience

Regulatory Status

Research Use Only