Search results for: 'Myc Reporter'

  • Citations   This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.  Search By Product Name or Catalog Number Name Title 10X HAT Assay Buffer (50095...
  • iPSC-Derived Cells Induced pluripotent stem cells (iPSC), pioneered by Nobel Prize winner Shinya Yamanaka, are generated by converting mature human somatic cells via expression of four critical transcription factors known as Yamanaka factors: Myc, Sox2, Klf4, and Oct3/4. iPSCs are an important tool for research because they are capable of differentiating into various cell types, including those of different tissues and organs. They can be used to study disease mechanisms, drug developm...
  • The Role of ADAR1 in Biology and Disease Adenosine deaminases acting on RNA (ADAR) proteins catalyze the post-transcriptional modification of adenosine to inosine (A-to-I) on double-stranded RNA (dsRNA) molecules. The ADAR proteins edit A to I non-selectively in extended perfect double-stranded RNA duplexes, an activity that is of ancient origin and highly conserved. ADAR1 functions as a major RNA editor, resulting in the differential regulation of RNA processing by other RNA-binding protein...
  • Research Applications for Engineered iPS Cells Introduction New avenues of research were dramatically opened by the discovery of Takahashi and Yamanaka in 2006 that the ectopic expression of Oct4 (octamer-binding transcription factor 4), Sox2 (SRY-box2), Kfl4 (Kruppel-like factor 4) and c-Myc was sufficient to reprogram terminally differentiated cells into induced pluripotent stem (iPS) cells. These have infinite expansion potential and similar genetic markers, epigenetics and multilineag...