iPSC-Derived Cells
Induced pluripotent stem cells (iPSC), pioneered by Nobel Prize winner Shinya Yamanaka, are generated by converting mature human somatic cells via expression of four critical transcription factors known as Yamanaka factors: Myc, Sox2, Klf4, and Oct3/4. iPSCs are an important tool for research because they are capable of differentiating into various cell types, including those of different tissues and organs. They can be used to study disease mechanisms, drug developm...
In Vitro Toxicity Research Solutions
In vitro toxicity testing plays a critical role in drug development by enabling early and efficient identification of potential safety concerns, reducing reliance on animal testing, and supporting regulatory requirements for drug approval.
In vitro toxicity testing plays a critical role in drug development by enabling early and efficient identification of potential safety concern...
Cell Cytotoxicity Screening & Profiling Services
Small Molecule Cell Cytotoxicity Assays
Understanding cell cytotoxicity, either as a result of targeted therapy or as a side effect, is important in drug development. Our expert scientists can help determine effective dose curves for your molecules of interest in whole cell assays, whether they are small molecules or biologics, including antibody drug conjugates. Over 30 different tumor cell lines are availabl...
Research Applications for Engineered iPS Cells
Introduction
New avenues of research were dramatically opened by the discovery of Takahashi and Yamanaka in 2006 that the ectopic expression of Oct4 (octamer-binding transcription factor 4), Sox2 (SRY-box2), Kfl4 (Kruppel-like factor 4) and c-Myc was sufficient to reprogram terminally differentiated cells into induced pluripotent stem (iPS) cells. These have infinite expansion potential and similar genetic markers, epigenetics and multilineag...
Media Components Table
For your cell culture needs, BPS Bioscience has developed an extensive selection of ready-to-use media products optimized for performance with our cell lines and cell-based assays. These media products are designed for either thawing, growth, or assaying cells. The table below outlines the specific components in each product, allowing you to compare products or choose the appropriate pre-made media option, freeing you from having to prepare your own media product wit...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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10X HAT Assay Buffer (50095...
