IDO/TDO Pathway
BPS Bioscience is a trusted provider and manufacturer of IDO pathway reagents, assay kits, cell lines and services. Cancer cells use the indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) pathways to suppress the host’s immune response in order to facilitate survival, growth, invasion, and metastasis of malignant cells. IDO enzymes and IDO-related enzymes are active in many tumors, providing a direct defense against T cell attack. I...