Bioactive Proteins & Enzymes
BPS Bioscience specializes in manufacturing bioactive enzymes and protein complexes, offering over 2000 protein products critical for drug discovery. We feature a large selection of epigenetic and metabolic enzymes, kinases and other cell signaling proteins, as well as cancer-related proteins and their mutants, including KRAS, PARP proteins, and immune checkpoint molecules. Contact us to learn how our products and services can help you reach your resea...
TIGIT, CD155, & CD226
Promising Targets for Cancer Immunotherapies
It’s possible someone you know has benefited from cancer treatments based on checkpoint receptors. Therapeutic antibodies targeting PD-1 and CTLA-4 pathways have already added years to the lives of lucky patients. Unfortunately, not everyone responds to these treatments. This resistance drives the search for new therapies to extend the successes of existing PD-1 and CTLA-4-based treatme...
Protein Frequently Asked Questions
FAQ Topic:
-Any-
General Questions
KRAS
FAQ Search:
How do I thaw recombinant proteins?
Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening the tube. Avoid multiple freeze/thaw cycles. Enzymes are particularly sensitive to freeze/thaw and may lose some activity if thawed again. When proteins are diluted to perform an assay do not freeze and re-use the diluted protein.
...
Epigenetics
Modulation of Gene Expression Without Changing the Genome
The field of epigenetics refers to the control or modulation of gene expression that produces a specific phenotype or trait without directly changing DNA sequences. Epigenetic control can occur by modifying DNA, RNA, or by modulating the proteins that bind to DNA, particularly histone proteins. Epigenetic modifications start early in embryonic development and continue as organisms age and are strongl...
CD39 & CD73: Adenosine Signaling
Therapeutic antibodies targeting checkpoint receptors such as PD-1 and CTLA4 are giving new hope to cancer patients. However, not all patients respond to treatment and the search for effective co-therapies is driving substantial research. Two critical enzymes of this pathway, CD39 and CD73 , are promising targets for increasing the effectiveness of checkpoint-based immunotherapies. 1
The hydrolysis of extracellular ATP to AMP is...
A2aR & Immunotherapy
The great need for treatments and the promise of cures are driving the search for second-generation immunotherapies beyond therapeutic antibodies targeting PD-1 and CTLA4 pathways. Immunotherapies are not limited to just therapeutic antibodies . Small-molecule inhibitors are showing great promise in clinical trials. For example, inhibitors targeting the enzymatic pathways, such as tryptophan catabolism are in late-phase clinical develop...
Frequently Asked Questions
BPS Bioscience is here to answer your questions and provide project guidance. On the following pages, we outline some of the most frequently asked questions separated by product type. If your question is not answered through these resources, please contact us today and we are happy to assist.
Proteins
Cell Lines
Assay Kits ...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
Search By Product Name or Catalog Number
Name
Title
10X HAT Assay Buffer (50095...
