Caspase7, His-tag Recombinant

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Catalog #

70000

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Description

Human Caspase-7 (full length) (GenBank Accession No. NM_001227) with C-terminal His-tag, MW= 35.1 kDa, expressed in an E. coli expression system. Active caspase 7 is a heterotetramer consisting of two copies each of ~20 kDa and ~11 kDa subunits.

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Synonyms

Caspase-7, CASP7, Caspase 7, Mch3, ICE-LAP3, Caspase

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Product Data Gallery

4-20% SDS-PAGE Coomassie staining

Specific Activity

Caspase-7 inhibition curve using a fluorogenic assay (#80701). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

E. coli

Purity

≥90%

Format

Aqueous buffer solution

Formulation

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 155 mM imidazole, 20% glycerol and 3 mM DTT.

35.1 kDa

Amino Acids

full length

Specific Activity

≥ 5337 pmol/min/µg

Genbank #

NM_001227

UniProt #

P55210

Tag(s)

C-terminal His-tag

Background

Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis.

References

Wang DH., et al., PLoS one,7(6):e39920. doi:10.1371/journal.0039920. (2012).

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Datasheets/Protocols

70000_Lot130116.pdf

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