AICAR
Catalog #
27049
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Description
AICAR, also known as acadesine, is an adenosine regulating agent and AMPK activator. AICAR was found to activate AMP-activated protein kinase (AMPK) in skeletal muscle, inhibit acetyl-CoA carboxylase, reduce malonyl-CoA, and increase fatty acid oxidation and glucose uptake. Note: This product is not 5'-phosphorylated.
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Synonyms
Acadesine, AIC -Riboside, 5-Aminoimidazole-4-carboxamide riboside
Product Info
Storage and Usage
Citations
Purity
≥99%
Format
Tan powder
Formula
C9H14N4O5
MW
258.2 Da
Solubility
Soluble in DMSO at 40 mg/ml; soluble in ethanol at 2 mg/ml with warming; soluble in water at 20 mg/ml with warming
CAS Registry #
2627-69-2
References
Merrill, G.F., et al. Am. J. Physiol. 273: E1107-E1112 (1997).