Sortase-Mediated Protein Ligation
Protein modification is a powerful tool for both research and medicine, and these modifications are of special importance to the research and drug discovery communities. Proteins modified with added fluorophores or other compounds are instrumental in studying cellular pathways and molecular mechanisms 1-4 . Additionally, antibodies conjugated with toxic cargos can be highly potent anti-tumor drugs 5-7 . At BPS, we specialize in num...
Bioactive Proteins & Enzymes
BPS Bioscience specializes in manufacturing bioactive enzymes and protein complexes, offering over 2000 protein products critical for drug discovery. We feature a large selection of epigenetic and metabolic enzymes, kinases and other cell signaling proteins, as well as cancer-related proteins and their mutants, including KRAS, PARP proteins, and immune checkpoint molecules. Contact us to learn how our products and services can help you reach your resea...
IDO/TDO Pathway
BPS Bioscience is a trusted provider and manufacturer of IDO pathway reagents, assay kits, cell lines and services. Cancer cells use the indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) pathways to suppress the host’s immune response in order to facilitate survival, growth, invasion, and metastasis of malignant cells. IDO enzymes and IDO-related enzymes are active in many tumors, providing a direct defense against T cell attack. I...
Support Products & Consumables
Off-the-Shelf Solutions and Kits for Cell and Protein Analysis
In scientific experimentation, even basic components such as buffers and reagents can have a significant influence on the integrity of experimental outcomes. Accurate preparation and proper selection of buffers are crucial for achieving consistent and reliable results. For instance, in processes like cell lysis, the choice of the appropriate buffer can ...
Protease Screening & Profiling
Proteases are catalytic enzymes found in all forms of life, including viruses, that regulate a wide range of vital physiological processes. In animals, they are critical for digestion of food, lysosome and proteasome degradation, apoptosis, blood coagulation, cell cycle regulation, cell signaling, and more. The dysregulation of protease activity can lead to pathologies such as arthritis and inflammatory diseases, cardiovascul...
ADC and Antibody-Based Cancer Therapies
Antibody-based therapies, such as antibody-drug conjugates (ADCs) and multi-specific T cell engager molecules, provide a targeted approach to treating cancers.
Antibody-based therapies, such as antibody-drug conjugates (ADCs) and multi-specific T cell engager molecules, provide a targeted approach to treating cancers.
Monoclonal antibodies, which are laboratory-produced molecules that bind to a specif...
Claudin-18: A Therapeutic Target in Oncology
Claudins, a family of small tetraspan proteins expressed in a tissue or cell-specific manner, are major components of the multimeric protein architecture of tight junctions, which prevent ions or small molecules from passing freely between epithelial or endothelial cells. These proteins contain four transmembrane domains mainly responsible for interacting side-to-side with neighboring proteins. Two extracellular loops regulate p...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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10X HAT Assay Buffer (50095...
