Spike S1 Neutralizing Antibody (SARS-CoV-2) (Clone: 414-1)

Catalog #
100793
$485 *
Size: 100 µg
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Description

Recombinant human monoclonal (clone 414-1) antibody recognizing the SARS-CoV-2 Spike S1 RBD glycoprotein. This antibody cross-reacts with the Spike protein from the SARS-CoV virus. Molecular Weight: 141 kDa (full length S1 protein).

This product has been cited 4 times.

Synonyms
Severe acute respiratory neutralizing antibody, Spike RBD neutralizing antibody, SARS-CoV antibody, SARS-CoV-2 antibody, nCoV antibody
Product Info
Storage and Usage
Citations4
Species
SARS-CoV-2
Isotype
IgG1
Clonality
Monoclonal
Host Species/Expression System
Human
Supplied As
Aqueous buffer solution.
Purification
Protein A Chromatography
Formulation

140 mM HEPES, pH 7.5, 70 mM NaCl, 32 mM NaOAc, 0.035% sodium azide, and 30% glycerol.

Specificity

This antibody cross-reacts with the Spike protein from the SARS-CoV virus.

Genbank #
QHD43416.1
Background

This antibody was derived from COVID-19 patients who have cleared the virus. Patient serum IgG was sequenced and expressed as full-length IgG1 with human immunoglobulin heavy and light chains in mammalian 293 cells.

References

1. Zhou P., et al., Nature. 2020; 579: 270-289.
2. Xiao X., et al., Cell Mol Life Sci. 2004; 61(19-20): 2428-2430.