SIRP-α (CD172a), His-tag (Human) Recombinant
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Catalog #
71145
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$95
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Description
Signal regulatory protein-alpha (SIRP-α), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal His-tag, MW 38.4 kDa*, expressed in a HEK293 expression system. This protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in apparent higher molecular weight.
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Synonyms
CD172A, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol
MW
38.4 kDa
Amino Acids
27-370
Genbank #
NM_080792
UniProt #
P78324
References
1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77
2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63