CAMK1δ, GST-tag Recombinant

Catalog #
40037
$410 *
Size: 10 µg
Qty
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Description

Recombinant human CAMK1δ, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Synonyms
RP11-462F15.1, CKLiK, CaM-K1, CaMKID, CAMK-1
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
≥75%
Format
Aqueous buffer solution
Formulation
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
MW
68 kDa
Amino Acids
full length
Genbank #
NM_153498
UniProt #
Q8IU85
Tag(s)
N-terminal GST-tag
Background
CAMK1δ or Ca2+/calmodulin-dependent kinase I-like kinase (CKLiK) is activated by Ca(2+) and calmodulin and is detected in CD34+-derived neutrophils and eosinophils, as well as in mature peripheral blood granulocytes (1). CAMK1δ exhibits Ca(2+)/CaM-dependent activity that is enhanced in vitro by phosphorylation of its Thr180 by CaM-K kinase (CaM-KK)alpha, consistent with detection of CAMK1D-activating activity in HeLa cells (2).
References
1. Verploegen, S. et al: Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function. Blood 106 (3), 1076-1083 (2005).
2. Ishikawa, Y. et al: Identification and characterization of novel components of a Ca2+/calmodulin-dependent protein kinase cascade in HeLa cells. FEBS Lett. 550 (1-3), 57-63 (2003).