Z-FA-FMK

Catalog #
27667-1
$290 *
Size: 5 mg
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Synonyms
Z-FA-FMK; Z-Phe-Ala fluoromethyl ketone; Cathepsin B Inhibitor
Product Info
Storage and Usage
Citations
Purity

≥95% by HPLC

Target(s)
cathepsins
Formula
C21H23N2O4F
MW
386.4 Da
Solubility
Soluble in DMSO
Biological Activity
We recommend using 2-10 µM for inhibiting non-caspase cysteine protease activity in cell culture, or as a control for other FMK caspase inhibitors. The optimal dose may vary for different cells and culture conditions.
CAS Registry #
197855-65-5
References
1. Lopez-Hernandez, F.J., et al. 2003. Mol. Cancer Ther. 2: 255-263.
2. Ahmed, N.K., et al. 1992. Biochem. Pharmacol: 44: 1201-1207.
3. Lawrence, C.P., et al. 2006. J. Immunol. 177: 3827-3826.