UNC669

Catalog #
27664-1
$145 *
Size: 10 mg
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Description

UNC669 is a potent and selective MBT (malignant brain tumor) inhibitor for L3MBTL1.

Synonyms
(5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
Product Info
Storage and Usage
Citations
Purity

≥98% by HPLC

Target(s)
L3MBTL1
Formula
C15H20BrN3O
MW
338.2 Da
Solubility
Soluble in DMSO
Biological Activity
Small molecule antagonist of methyl-lysine (KMe) reader protein with selectivity for L3MBTL1 and L3MBTL3 (IC50 of 4.2 µM and 3.1 µM respectively). An earlier publication reported a 5- and 11-fold selectivity of L3MBTL1 (IC50 = 6 µM )over L3MBTL3 (IC50 = 35 µM )and L3MBTL4 (IC50 > 70 µM).
CAS Registry #
1314241-44-5