CBL-B (Y363F), His-tag, Biotin-labeled (Human)

Catalog #: 80413
Size: 50 µg
$370
Species: Human
Host Species: E. coli
MW: 48 kDa
Genbank #: NM_170662
Tag(s): N-terminal His-tag, N-terminal Avi-tag
a.a: 39 – 426
Description:

Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B), also known as E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, and SH3- binding protein CBL-B with Y363F mutation GenBank Accession No. NM_170662, a.a. 39 – 426 with N-terminal His-tag and N-terminal Avi-tag, expressed in an E. coli expression system. This protein was enzymatically biotinylated in vivo using AviTagTM technology. MW=48 kDa.

UniProt
Q13191
Synonym(s):
E3 ubiquitin-protein ligase CBL-B, RING finger protein 56, SH3-binding protein CBL-B with Y363F mutation, CBL
Formulation:
40 mM Hepesl, pH 7.4, 120 mM NaCl, 20% glycerol, 200 mM imidazole
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C
Application(s):
Useful for the study of enzyme kinetics and regulation, to dephosphorylate target substrates and for screening inhibitors.
Reference(s):
1. Jeon, M.S., et al., Immunity. 2004; 21(2): 167-177.
2. Chiang, Y.J. et al., Nature. 2000; 403: 216-220.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Ubiquitin E3 ligase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance

Product Datasheets

80413_Lot150430.pdf