Tofacitinib

Catalog #

27037

$170 *

Size: 25 mg

Qty

Bulk/Custom

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Description

Tofacitinib, also known as Tasocitinib, is a novel inhibitor of Janus kinase 3 (JAK3), a critical cytoplasmic tyrosine kinase in the signaling pathways of multiple cytokines. Research suggests Tofacitinib acts as an immunosuppressant, preventing organ transplant rejection, and that it has potential to alleviate symptoms of autoimmune diseases, such as rheumatoid arthritis and psoriasis.

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Synonyms

CP-690550, Tasocitinib

Product Info

Storage and Usage

Citations

Purity

≥99%

Format

White to off-white solid.

Formula

C₁₆H₂₀N₆O

312.4 Da

Solubility

Soluble in DMSO at 100 mg/ml; soluble in ethanol at 100 mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20 µM

CAS Registry #

477600-75-2

References

West, K. Curr. Opin. Investig. Drugs 10: 491-504 (2009).

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Tofacitinib

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