TDO, His-Tag (Human) Recombinant
Catalog #
71195
$350
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Description
Recombinant human TDO2 (tryptophan 2,3-dioxygenase) full length encompassing amino acids 2-406 (end). This construct contains an N-terminal His-Tag (6xHis). The protein was affinity purified.
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Synonyms
Tryptophan 2,3-dioxygenase, TDO2, TDO-2, TO, TDO, TPH2, TRPO, HYPTRP, Tryptamin 2,3-dioxygenase, Tryptophan pyrrolase, Tryptophanase
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Construct
TDO (His-2-406(end))
Host Species/Expression System
E. coli
Purity
≥85%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween 20, 20% glycerol, 250 mM Imidazole
MW
49 kDa
Amino Acids
2-406(end)
Genbank #
NM_005651
UniProt #
P48775
References
1. Pillotte, L., et al., Proc. Nat. Acad. Sci (USA). 2012; 109(7):2497-2502.
2. Miller, C.L., et al., Neurobiol. Disease. 2004; 15(3): 618-629.
Application Reference(s):
1. Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophan 2, 3-dioxygenase (TDO) (2019)