Sitagliptin

Catalog #

27106

$235 *

Size: 200 mg

Qty

Bulk/Custom

*US Pricing only. For international pricing, please contact your local distributor.

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Description

Sitagliptin, also known as MK-0431 and Januvia, is a Dipeptidyl Peptidase IV Inhibitor.

This product has been cited 2 times.

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Synonyms

Sitagliptin, MK-0431, Januvia

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Product Data Gallery

Product Info

Storage and Usage

Citations2

Purity

≥98% by NMR

Format

White to beige powder.

Formula

C₁₆H₁₅F₆N₅O•H₃PO₄

505.3 Da

Solubility

Soluble in DMSO.

Biological Activity

Sitagliptin as a DPP-4 inhibitor has IC50 value of 18 nM when testing treatment of patients with type 2 diabetes mellitus.

CAS Registry #

654671-78-0

References

1. Gallwitz B. Drugs Today (Barc). 2007 Nov; 43(11):801-14
2. Su-Jin Kim et al. Diabetes, 2010 July; 59(7):1739-1750