Sitagliptin

Catalog #: 27106
Size: 200 mg
$230
MW: 505.3 Da
CAS Registry #: 654671-78-0
Formula: C16H15F6N5O•H3PO4
Description:
Sitagliptin, also known as MK-0431 and Januvia, is a Dipeptidyl Peptidase IV Inhibitor.
Synonym(s):
Sitagliptin, MK-0431, Januvia
Purity:

≥98% by NMR

Biological Activity:
Sitagliptin as a DPP-4 inhibitor has IC50 value of 18 nM when testing treatment of patients with type 2 diabetes mellitus.
Solubility:
Soluble in DMSO.
Format:
White to beige powder.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Gallwitz B. Drugs Today (Barc). 2007 Nov; 43(11):801-14
2. Su-Jin Kim et al. Diabetes, 2010 July; 59(7):1739-1750
Scientific Category:
DPP
Product Type:
Inhibitor
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Product Datasheets

27106_Lot111121.pdf