CD47 Screening Services
Cluster of Differentiation 47, or CD47, plays an essential role in cell growth, death, migration, and adhesion. CD47 binding to SIRP-α mediates phagocytosis by sending a “do not eat me” signal to phagocytes. CD47 proteins are often over expressed by tumor cells as a means for them to escape phagocytosis. As a result, cancerous tumor cells have the ability to proliferate and evade the immune system.
BPS Bioscience offers CD47:SIRP-α and CD47:SIRP-ɣ screening services to help accelerate your research and drug discovery programs. This biochemical screen is a fast, reliable, and inexpensive initial screen to identify inhibitors of CD47 binding to SIRP-α and/or SIRP-ɣ. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio make it easy to:
- Screen for inhibitors/targets using our CD47:Sirpα assay
- Select from IC50 determination and single point concentrations
- Receive data within days of compound submission
- Perform follow-up studies using the same soluble receptors manufactured in-house
Get questions answered or project guidance in a time-efficient manner. BPS Biosciences offers a variety of CD47 related products, including
Contact BPS today to find out more about how we can assist you in your CD47 related research.
Not quite what you're looking for? We also offer custom assays for several other immunotherapy targets. Our Custom Assay Development Services allow for flexibility to meet your specific research needs
Want to Streamline Your Project?
Looking for more?