Anti-PD-1 Neutralizing Antibody, PE-labeled

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Catalog #
71290
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Description

R-Phycoerythrin-labeled anti-PD-1 neutralizing recombinant murine/human chimeric antibody recognizing the PD-L1/PD-L2 binding region of human PD-1.

Synonyms
Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L
Product Info
Storage and Usage
Citations
Species
Murine/Human
Isotype
IgG1K
Clonality
Monoclonal
Host Species/Expression System
HEK293
Purity

≥90%

Purification
Protein A affinity chromatography from HEK293 supernatants.
Formulation

8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol

MW
Heavy Chain: 49 kDa + glycans + PE, Light Chain: 23 kDa + PE
UniProt #
Q15116
Label
R-Phycoerythrin (PE) is an oligomeric protein complex (270 kDa) from red algae that exhibits intensely bright red-orange fluorescence with high quantum yields. The complex consists of six heterodimers, α subunit (18 kDa) and β-subunit (20 kDa), and an additional γ-subunit (34 kDa). PE is covalently attached randomly through lysines on the target protein.
References

1. Shinohara, T., et al., Genomics. 1994 Oct;23(3):704-6.
2. James, E.S., et al., Genes Immun. 2005 Aug;6(5):430-7.