Rheb, His-tag Recombinant
Catalog #
45100
$385
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Description
Human Rheb (GenBank Accession No. NM_005614), full length with N-terminal His-tag, MW=23 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
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Synonyms
Ras Homolog Enriched In Brain, Rheb
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
MW
23 kDa
Amino Acids
full length
Genbank #
NM_005614
UniProt #
Q15382
Background
Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
References
1. Karbowniczek,M. et al. Biol. Chem. 281 (35), 25447-25456 (2006).
2. Buerger,C. et al. Biochem. Biophys. Res. Commun. 344 (3), 869-880 (2006).
2. Buerger,C. et al. Biochem. Biophys. Res. Commun. 344 (3), 869-880 (2006).