Renin, His-tag

Catalog #: 80200
Size: 100 µg
$420
Species: Human
Host Species: HEK293 cells
MW: 38.6 kDa
Genbank #: NM_000537
Tag(s): C-terminal His-tag
a.a: 67–406
Background:
Renin is a protease that is synthesized by the kidneys. Renin catalyzes the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the treatment of hypertension (high blood pressure).
Description:
Human Activated Renin (GenBank Accession No. NM_000537), amino acids 67 - 406 (end) with C-terminal HIS tag, MW=38.6 kDa, expressed in a mammalian expression system.
UniProt
P00797
Synonym(s):
Angiotensinogenase, Renin Protein, Renin his tag, Renin protease, renin , renin angiotensin aldosterone system, renin angiotensin aldosterone
Specific Activity:
≥ 255 pmol/min/µg.
Assay Conditions:
Assay was performed using BPS's Renin Assay kit, cat. # 80211, following the recommended assay protocol.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 250 mM imidazole, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C.

Reference(s):

1. Cho, M.J., et al., J Pediatr Endocrinol Metab. 2011; 24(11-12):1085 – 1087
2. Schnermann, J., et al., Kidney Int. 2012 Mar; 81(6): 529 – 538

Application Reference(s):
1. Rapid Screening of Primary Aldosteronism by a Novel Chemiluminescent Immunoassay (2017)

Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Protease
Product Type:
Recombinant Protein
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Product Datasheets

80200_Lot120228.pdf