PTPIA2(PTPRN), GST-tag Recombinant

Catalog #
30054
$325 *
Size: 50 µg
Qty
*US Pricing only. For international pricing, please contact your local distributor.
Purchase
Description

Pseudophosphatase PTP-IA2, also known as PTPRN and ICA-512, GenBank accession no. NM_002846, a.a. 693- 979, with an N-terminal GST-tag, MW=58.8 kDa, expressed in an E. coli expression system.

Synonyms
PTP-IA2, ICA-512, PTPRN, Islet Cell Antigen 2, IA2
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥90%

Format
Aqueous buffer solution
Formulation
25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, and 10 mM glutathione.
MW
58.8 kDa
Amino Acids
693–979
Genbank #
NM_002846
UniProt #
Q16849
Tag(s)
N-terminal GST-tag
Background
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
References
1. T. Ort et al., EMBO J. 2001, 20: 4013-23.
2. Z. Li et al., J Histochem Cytochem. 2000, 48:761-7.