DPP9, GST-Tag

Catalog #: 80090
Size: 10 µg
$425
Species: Human
Host Species: Sf9 insect cells
MW: 124 kDa
Genbank #: NM_139159
Tag(s): N-terminal GST-tag
a.a: full length
Background:
Dipeptidyl peptidase-9 (DPP9) is a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. DPP9 exhibits similar activity to that of DPP4 but unlike DPP4, DPP9 is not membrane bound. DPP9 activity has been linked to several diseases, including type 2 diabetes, obesity and cancer.
Description:

Human DPP9 (GenBank Accession No. NM_139159), full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

UniProt
Q86TI2
Synonym(s):
Dipeptidylpeptidase 9, DPPIX, DPP9 Protein, DPP
Specific Activity:
≥ 536 pmol/min/µg
Assay Conditions:
25 mM Tris HCl, pH 7.5, 0.1% BSA, 5 µM substrate (H-Gly- Pro-AMC), and DPP9. Incubation condition: 1 min. at room temperature.
Formulation:
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 18 mM glutathione, 10% glycerol, and 3 mM DTT.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C.

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Bjelke,J.R. et al., Biochem. J. 396 (2), 391- 399 (2006).
2. Yu, D.M. et al., FEBS J. 273 (11), 2447-2460 (2006).

Application Reference(s): 
1. ZY15557, a novel, long acting inhibitor of dipeptidyl peptidase-4, for the treatment of Type 2 diabetes mellitus (2017)

Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Protease
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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Product Datasheets

80090_Lot2000.pdf