ME0328
Catalog #
27634-1
$140
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Description
ME0328 is a potent and selective PARP inhibitor with about 7-fold selectivity over PARP3 over PARP1.
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Synonyms
3-(4-oxo-1H-quinazolin-2-yl)-N-[(1S)-1-phenylethyl]propanamide
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Product Data Gallery
Product Info
Storage and Usage
Citations
Purity
≥98% by HPLC
Target(s)
PARP3
Formula
C19H19N3O2
MW
321.4 Da
Solubility
Soluble in DMSO
Biological Activity
ME0328 is a potent and selective PARP3 inhibitor with IC50 of 0.89 µM for PARP3, vs. 6.3 µM for PARP1.
CAS Registry #
1445251-22-8
References
Lindgren, A.E., et al. ACS Chem Biol. 2013 Aug 16;8(8):1698-703.