Cilomilast

Catalog #
27742-1
$150 *
Size: 5 mg
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Description

Cilomilast, also known as SB-207499 or Ariflo, is a potent second generation inhibitor of type 4 phosphodiesterase (PDE4), an enzyme metabolizing cellular cyclic adenosine monophosphate (cAMP) which acts as a second messenger to disrupt the function of inflammatory cell and induce airway smooth muscle relaxation.

Synonyms
Cilomilast; SB-207499; Ariflo
Product Info
Storage and Usage
Citations
Target(s)
PDE4
Formula
C20H25NO4
MW
343.4 Da
Solubility
Soluble in DMSO
CAS Registry #
153259-65-5
References
1. M Profita, et al. Thorax 2003; 58: 573-579.
2. Barry D. et al. J Clin Pharmacol 2001; 41: 950-958.