PD-1 (K78A), Fc fusion, Biotin-labeled (Human) HiP™ Recombinant

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Catalog #
71244
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Description

Human secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_005018, a.a. 25-167 with a K78A mutation, fused at the Cterminus with the Fc portion of human IgG1, and C-terminal AviTag™, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using AviTag™ technology. MW = 44.5 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Synonyms
Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity

≥90%

Format
Aqueous buffer solution
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
MW
44.5 kDa+glycans
Amino Acids
25-167
Genbank #
NM_005018
UniProt #
Q15116
Tag(s)
C-terminal AviTag™
Label

This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation confirmed to be ≥90%.

For more information on enzymatic biotinylation, please see our Tech Note

References

1. Freeman, G.J., et al., J. Exp. Med. 2000 Oct 2; 192(7):1027-34.
2. Dong, H., et al., Nat Med. 1999 Dec; 5(12):1365-9.