Otub1, His-tag Recombinant
Catalog #
81088
$315
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Purchase
Description
Human Otub1 recombinant protein, with His-tag, expressed in E. coli.
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Synonyms
Deubiquitinating enzyme OTUB1, FLJ20113, FLJ40710, HSPC263, MGC111158, OTB1, OTU1, Otubain 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Ubiquitin-specific-processing protease OTUB1, Ubiquitin thioesterase protein OTUB1
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥95% by SDS-PAGE
Format
Aqueous buffer solution
MW
32 kDa
UniProt #
Q96FW1
Background
Otubain 1 is a member of the OTU (ovarian tumor) class of ubiquitin isopeptidases. It was originally identified as a protein capable of binding ubiquitin aldehyde.Researchers have shown that it is able to cleave K48-linked ubiquitin chains in vitro.Otubain 1 has been shown to be involved in T cell function and is a substrate for Yersinia protein kinase.
References
1. Juris, S.J., et al. FEBS Lett. 2006. 581(1):179-183.
2. Soares, L., et al. Nat. Immunol. 2004. 51(1):45-54.
3. Balakirev, M. et al. EMBO Rep. 2003. 4(5): p517-522.
2. Soares, L., et al. Nat. Immunol. 2004. 51(1):45-54.
3. Balakirev, M. et al. EMBO Rep. 2003. 4(5): p517-522.