NSD3 (1021-1322) (WHSC1L1), GST-tag

Catalog #: 51036
Size: 50 µg
$375
Species: Human
Host Species: E. coli
MW: 61 kDa
Genbank #: NM_023034
Tag(s): N-terminal GST-tag
a.a: 1021–1322
Background:
NSD3 is a histone methyltransferase that preferentially methylates Lys4 and Lys27 of histone H3. Lys4 methylation usually represents a specific tag for epigenetic transcriptional activation, while Lys27 is a mark for transcriptional repression.
Description:
Human Nuclear SET domain-containing protein 3 (NSD3), also known as WHSC1L1, GenBank Accession No. NM_023034, a.a. 1021-1322, with N-terminal GST-tag, MW=61 kDa, expressed in an E. coli expression system.
UniProt
Q9BZ95
Synonym(s):
WHSC1L1, Protein Whistle, NSD3, Nuclear SET Domain-Containing Protein 3, Wolf-Hirschhorn syndrome candidate 1-like 1, NSD
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 3 mM DTT and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C.

Application(s):
Suitable for protein binding studies, as an immunogen, or as a Western blotting control.
Reference(s):
1. Morishita, M., di Luccio E., Biochim Biophys Acta. 2011 Dec,1816(2):158-63.
2. Rahman, S., et al., Mol Cell Biol. 2011 Jul,31(13):2641-52.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Methyltransferase
Product Type:
Recombinant Protein
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Product Datasheets

51036_Lot130220-E1.pdf