NcoR2 (SMRT), GST-tag Recombinant

Catalog #

50020

$420 *

Size: 50 µg

Qty

Bulk/Custom

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Description

Human NCOR2/SMRT, DAD domain, a.a. 395-489, GenBank Accession No. NM_006312, N-terminal GST-tag, MW= 39 kDa, expressed in E. coli system. Source: E. coli. Purity: > 60% by SDS-PAGE.

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Synonyms

nuclear receptor corepressor 2, Silencing mediator of retinoic acid and thyroid hormone receptor, TRAC-1, SMRT, NcoR2

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

E. coli

Format

Aqueous buffer solution

Formulation

50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 20 mM glutathione, and 10% glycerol.

39 kDa

Amino Acids

395–489

Genbank #

NM_006312

UniProt #

Q9Y618

Tag(s)

N-terminal GST-tag

Background

NcoR2 , nuclear receptor corepressor, are transcriptional corepressors that play an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain , DAD, of NCOR2/SMRT is required for activation of the otherwise inert deacetylase.

References

Codina, A. et al., Proc. Natl. Acad. Sci. USA, 102, 6009-6014, (2005)

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NcoR2 (SMRT), GST-tag Recombinant

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