NAMPT (PBEF1) Recombinant
Catalog #
71098
$460
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Description
Human Nicotinamide phosphoribosyltransferase protein (NAMPT), also known as PBEF1 or visfatin (GenBank Accession No. NM_005746), a.a. 2-491 (end), no tag, MW=56 kDa, expressed in an E. coli cell expression system.
This product has been cited 1 time.
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Synonyms
Nicotinamide phosphoribosyltransferase protein, NAMPT, PBEF1, visfatin, Pre-B Cell-Enhancing Factor
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Product Data Gallery
4-20% SDS-PAGE Coomassie Staining
NAMPT Activity
Product Info
Storage and Usage
Citations1
Species
Human
Construct
NAMPT (PBEF1) (2-491(end))
Host Species/Expression System
E. coli
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.
MW
56 kDa
Amino Acids
2–491
Specific Activity
≥2 pmol/min/µg
Genbank #
NM_005746
UniProt #
P43490
Background
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging.
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