PD-L1, Fc Fusion, PE-Labeled (Mouse) Recombinant

Catalog #
71268
$435 *
Size: 50 μg
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Description

Mouse PD-L1 (Programmed Death-Ligand 1), also known as CD274 or B7-H1, encompassing amino acids 18 to 238. This construct has a mouse IgG2a Fc domain on the C-terminus and has been labeled with PE. The recombinant protein was affinity purified.

Synonyms
Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1)
Product Info
Storage and Usage
Citations
Species
Mouse
Construct
mPD-L1 (18-238-Fc(mlgG2a))-(PE)
Host Species/Expression System
HEK293
Purity

≥90%

Format

Aqueous buffer solution.

Formulation

8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

MW
51 kDa + glycans + PE
Amino Acids
18-238
Glycosylation
This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Genbank #
NM_021893
Tag(s)
FC Fusion, PE Labeled
Label

R-Phycoerythrin (PE) is an oligomeric protein complex (270 kDa) from red algae that exhibits intensely bright red-orange fluorescence with high quantum yields. The complex consists of six heterodimers, α subunit (18 kDa) and β-subunit (20 kDa), and an additional γ-subunit (34 kDa). PE is covalently attached randomly through lysines on the target protein.

References
1. Brahmer, S., et al., N Engl J Med. 2012 Jun;366: 2455-2465

2. Powels, T., et al., Nature. 2000 Oct; 515(7528):558-562.