DNMT3a, GST-tag

Catalog #: 51103
Size: 10 µg
$445
Species: Human
Host Species: Sf9 insect cells
MW: 128 kDa
Genbank #: NM_175629
Tag(s): N-terminal GST-tag
a.a: 1–913 (end)
Description:
Human DNMT3a (GenBank Accession No. NM_175629), full length with N-terminal GST-tag, MW=128 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
UniProt
Q9Y6K1
Formulation:
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 18 mM glutathione, and 10% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at –80°C.

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Shikauchi, Y. et al., Mol. Cell. Biol. 29 (7):1944-1958 (2009).
2. Zhao, Q. et al., Nat. Struct. Mol. Biol. 16 (3):304-311 (2009).

Application Reference(s):
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases (2013)

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Methyltransferase
Product Type:
Recombinant Protein
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Product Datasheets

51103_Lot150106-a.pdf