LAG3 (CD223), Fc fusion (Human)

Catalog #: 71146
Size: 100 µg

$310
Species: Human
Host Species: HEK 293 cells
MW: 73.1 kDa
Genbank #: NM_002286
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 23-450
Description:

Human secreted LAG3, Fc fusion protein, also known as Lymphocyte-Activation Gene 3 and CD223. GenBank Accession No. NM_002286, a.a. 23-450 expressed in a HEK293 cell expression system. MW = 73.1 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
P18627
Synonym(s):
Lymphocyte-Activation Gene 3, CD223, Lag, Lag-3
Endotoxin Level:

<1 EU/µg

Formulation:
40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C.
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):
1. Byrnes, et al.. Cytometry A. 2012 Sep;81(2):165-8.
2. Di, Carlo., et al., J. Pathol. 2005 Jan; 205(1):82-91.

Notes:
The aggregation state of this product has been confirmed to be <10%.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance

Product Datasheets

71146_Lot140422.pdf