L3MBTL3, GST-tag Recombinant
Catalog #
55013
$460
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Description
Human lethal(3) malignant brain tumor-like protein 3 (L3MBTL3), GenBank Accession No. NM_032438, a.a. 229-547 with N-terminal GST-tag, MW = 63.6 kDa, expressed in an E. coli cell expression system.
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Synonyms
lethal(3) malignant brain tumor-like protein 3
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 1.8 mM glutathione, 0.007% Tween-20, and 20% glycerol.
MW
63.6 kDa
Amino Acids
229–547
Genbank #
NM_032438
UniProt #
Q96JM7
Background
PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
References
1. James, L.I., et al., Nat Chem Biol.
2013 Mar;9(3):184-91.
2. Arai, S., Miyazaki, T., EMBO J. 2005
May 18;24(10):1863-73.