L3MBTL1 TR-FRET Assay Kit

Catalog #

55200

$535 *

Size: 384 reactions

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

The L3MBTL1 TR-FRET Assay Kit is designed to measure the inhibition of L3MBTL1 binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing terbium-labeled donor, dye-labeled acceptor, L3MBTL1, substrate, and an inhibitor is incubated for sixty minutes. Then, the fluorescence intensity is measured using a fluorescence reader.

Need us to run inhibitor screens or profile your compounds against L3MBTL1? Check out our Methyl-lysine Reader Screening Services or DNA Replication & Repair Screening Services.

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Synonyms

L3MBTL1 assay kit

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Product Data Gallery

Product Info

Storage and Usage

Citations

Assay Kit Format

TR-FRET

Format

COMPONENTS

UniProt #

Q9Y468

References

Min, J., et al., Nat Struct Mol Biol.2008 Jan,15(1):114

Storage/Stability

Stable at least 6 months from date of receipt, when stored as directed

Instructions for Use

See data sheet for detailed protocol.

Applications

Useful for the study of MBT domain binding assays, screening inhibitors, and selectivity profiling

Shipping Temperature

-80°C (dry ice)

Contraindications

DMSO >1%, strong acids or bases, ionic detergents, high salt

Warnings

Avoid freeze/thaw cycles

Disclaimers and Limitations

BPS Bioscience assay kits are validated using the listed components according to our specific protocol. Any deviations to kit components or protocols, such as using different proteins, cell/tissue lysates, or buffers (including using the same component from other commercial sources) will void any warranties on the performance of the assay kit and is not recommended.

End-users should immediately report any issues to [email protected] upon receipt of the kit, such as missing components, damaged vials, no dry ice, etc.

Scientific Category

Methyl-lysine Reader

Regulatory Status

Research Use Only

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L3MBTL1 TR-FRET Assay Kit

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