Ruxolitinib Phosphate

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Catalog #

27059

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Description

INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor. (IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively). INCB018424 is useful for rheumatoid arthritis.

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Synonyms

INCB018424 phosphate, INCB 018424 phosphate, INCB-018424 phosphate, Ruxolitinib, 27059-1, 27059-2

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Product Info

Storage and Usage

Citations

Purity

≥98% determined by HPLC

Format

Solid

Formula

C₁₇H₂₁N₆O₄P

404.36

Solubility

≥20.2 mg/mL in DMSO; ≥6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.03 mg/mL in H2O with gentle warming and ultrasonic

CAS Registry #

1092939-17-7

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Ruxolitinib Phosphate

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