PI-103
Catalog #
27502-2
$325
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Description
PI-103 is a multi-targeted inhibitor of PI3K for p110, p110, p110 , and p110 with reported IC50 values of 2 nM, 3 nM, 3 nM, and 15 nM respectively. PI-103 is less potent towards mTOR/DNA-PK with reported IC50 values of 30 nM and 23 nM respectively.
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Product Info
Storage and Usage
Citations
Purity
≥98%
Format
Crystalline solid
Formula
C19H16N4O3
MW
348.36 kDa
Solubility
Soluble in DMSO or DMF at approximately 10 mg/ml. Poorly soluble in aqueous
solutions. If necessary, first solubilize in DMSO or DMF and dilute into an aqueous solution,
such as PBS.
CAS Registry #
371935-74-9
References
1. Zou, Z.Q., et al., Int. J. Mol. Med. 2009; 24(1): 97-101.
2. Lopez-Fauqued, M. et al., Int. J. Canc. 2010; 126(7): 1549-1561.
2. Lopez-Fauqued, M. et al., Int. J. Canc. 2010; 126(7): 1549-1561.
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