VEGFR2 (KDR) Kinase Assay Kit

Catalog #: 40325
Size: 96 reactions
$495
Description:
Vascular endothelial growth factor receptor 2 (VEGFR2), also called Kinase insert Domain receptor (KDR), is a tyrosine kinase (TK) receptor for VEGFs that plays a central role in tumor angiogenesis; therefore the inhibition of VEGFR2 is a promising therapeutic strategy for inhibiting angiogenesis and tumor growth. The VEGFR2 Kinase Assay Kit is designed to measure VEGFR2 kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Synonym(s):
kdr, Kinase Insert Domain Receptor, VEGFR2, Vascular Endothelial Growth Factor Receptor 2, CD309, FLK-1, Fetal Liver Kinase 1 KDR
Supplied As:
The VEGFR2 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant VEGFR2 enzyme, VEGFR2 substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Format:

Instructions for use:
See assay kit data sheet for detailed protocol.
Storage / Stability:
Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Application(s):
Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s):

Sharma, K., et al. Biomed Chromatogr. 2015 Jun; 29(6):803-34.

Fontanella, C., et al. Ann Transl Med. 2014 Dec; 2(12):12

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Kinase
Product Type:
Assay Kit
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Product Datasheets

40325.pdf