EGFR(L858R) Kinase Assay Kit

Catalog #: 40324
Size: 96 reactions
The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cell-surface receptor for members of the epidermal growth factor family. Overexpression and/or hyperactivation of EGFR kinase is associated with several human cancers such as lung, glioblastoma, and epithelian tumors of the neck and head, leading to the development of anticancer therapeutics targeting EGFR. EGFR(L858R) mutation is found in ~40% of EGFR-mutated lung tumors. The EGFR(L858R) Kinase Assay Kit is designed to measure EGFR (L858R) Kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
EGFR, ErbB-1, HER1
Supplied As:
The EGFR (L858R) Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant EGFR(L858R) enzyme, EGFR substrate, ATP and kinase assay buffer for 100 enzyme reactions.

Instructions for use:
See assay kit data sheet for detailed protocol
Storage / Stability:
Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

1. Nakamura, J.L. Expert Opin. Ther. Targets 11(4):463-472 (2007)

2. Tsai, M-F., et al. Scientific Reports 5: 13574 (2015)

Avoid freeze/thaw cycles.
Scientific Category:
Product Type:
Assay Kit
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