CDK5 Assay Kit

Catalog #

79600

$535 *

Size: 96 Reactions

Qty

Bulk/Custom

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*US Pricing only. For international pricing, please contact your local distributor.

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Description

CDK5 is an unconventional member of the CDK family. It is expressed in post-mitotic neurons, and its activity is regulated by neuron-specific activators p35/p25 and p39 rather than the cyclins. It has been suggested that CDK5 plays several roles in the nervous system, including Tau aggregation and tangle formation. The CDK5 Assay Kit is designed to measure CDK5 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.

This product has been cited 2 times.

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Synonyms

CDKN5, cyclin-dependent kinase 5, cyclin dependent kinase 5, CDK-5

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Product Data Gallery

Product Info

Storage and Usage

Citations2

Assay Kit Format

Luminescent

Supplied As

The CDK5 Assay Kit comes in a convenient 96-well format, with enough purified recombinant CDK5/p25 enzyme, CDK substrate peptide, ATP and kinase assay buffer for 100 enzyme reactions.

Format

Assay Kit Components

UniProt #

Q00535 (CDK5), Q15078 (p35)

References

Uzma A. et. al., Nature Review Drug Discovery 14:130-146 (2015)

Storage/Stability

Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Instructions for Use

See assay kit data sheet for detailed protocol.

Shipping Temperature

-80°C

Warnings

Avoid freeze/thaw cycles.

Disclaimers and Limitations

BPS Bioscience assay kits are validated using the listed components according to our specific protocol. Any deviations to kit components or protocols, such as using different proteins, cell/tissue lysates, or buffers (including using the same component from other commercial sources) will void any warranties on the performance of the assay kit and is not recommended.

End-users should immediately report any issues to [email protected] upon receipt of the kit, such as missing components, damaged vials, no dry ice, etc.

Scientific Category

Kinase

Regulatory Status

Research Use Only