KEAP1, His-Tag Recombinant

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Catalog #
70040
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Description

Human Keap1, also known as Kelch-like ECH-associated protein, INRF2, KIAA0132, and KLHL19, GenBank Accession No. NM_203500, a.a. 321-609 expressed in an E. coli cell expression system. MW = 32.6 kDa

Synonyms
Kelch-like ECH-associated protein, INRF2, KIAA0132, KLHL19, Nrf
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥80%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT and 20% glycerol.
MW
33 kDa
Amino Acids
321-609
Genbank #
NM_203500
UniProt #
Q14145
Tag(s)
His-tag
References

1. Dinkova-Kostova, A.T., et al., 2002. Proc. Nat. Acad. Sci. (USA). 99(18): 11908-11913.
2. Inoyama, D., et al. 2012. J. Biomol. Screening 17(4): 435-447.

Application References:

1. Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson\'s disease animal model