JosD1, His-tag Recombinant
Catalog #
81085
$410
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Description
Recombinant human full length JosD1. The construct contains an N-terminal His-Tag. The protein was affinity purified and is active.
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Synonyms
dJ508I15.2, Josephin-1, KIAA0063
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Construct
JosD1 (His-1-202(end))
Host Species/Expression System
E. coli
Purity
≥90% by SDS-PAGE
Format
Aqueous buffer solution
Formulation
50 mM Tris pH 8.0, 150 mM NaCl, 10% glycerol
MW
23 kDa
Amino Acids
1-202(end)
UniProt #
Q15040
Background
JOSD1 (Josephin-1) is a josephin domain-containing protein that has a deubiquitinase activity in vitro. Josephin domain-containing 1, often abbreviated as JOSD1, is a human gene that encodes a protein with a Josephin domain, which is a type of cysteine protease that can remove ubiquitin from other proteins. JOSD1 has been implicated in various studies to promote cancer cell growth and regulate membrane dynamics, cell motility, and endocytosis.
References
N. Tzvetkov and P. Breuer. Josephin domain-containing proteins from a variety of species are active de-ubiquitination enzymes. Biol. Chem. 2007. 388: p973-978.