JAK2 (V617F) (JH1, JH2 Domain), GST-Tag, Avi-Tag, Biotin-Labeled (Dephosphorylated) Recombinant
Catalog #
79115
$355
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Description
Human Jak2 containing the catalytic and the pseudo kinase domain, also known as Janus kinase-2, Just Another Kinase 2, Jak-2-JH1 and JH2, GenBank Accession No. NM_004972, a.a. 513-1132(end), with V617F mutation; with N-terminal GST-Tag and C-terminal Avi-Tag, co-expressed with PTP1B for dephosphorylation in HEK293 expression system. This protein is enzymatically Biotin-labeled using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%. MW=100 kDa.
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Synonyms
JAK2, Janus kinase-2, Just Another Kinase 2, V617F, jh1
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity
≥8%
Supplied As
Aqueous buffer solution.
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 16 mM Glutathione, 3 mM DTT, 20% glycerol.
Concentration
0.2 mg/ml
MW
100 kDa
Amino Acids
513-1132 (end)
Genbank #
NM_004972
UniProt #
O60674
References
1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.
2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.