(+)-JQ1
Catalog #: 27400

Size: 10 mg
Contact us for bulk (or custom) sizes at info@bpsbioscience.com.

Structure: 

CAS Registry #: N/A

Purity:  ≥95%

Chemical Formula: C₂₃H₂₅ClN₄O₂S

Molecular Weight: 456.99

Description: (+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs,
including the BRD2, BRD3, BRD4 and BRDT bromodomains.

Appearance: A crystalline solid.

Solubility: Soluble in DMSO or ethanol; insoluble in water.

Biological Activity: (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and
BRD4 (BD2) with a Kd of 90 nM.

Storage/Stability: Store at or below +4°C.

Quality Control: The purity was determined by HPLC.

Reference(s): Filippakopoulos P., et al. Nature. 468(7327):1067-73 (2011).

PRODUCT DATA SHEETS
Lot 120423

Data shown is lot-specific. For specific information on other lots, please contact us.

Manufactured, marketed and sold with authorization from Tensha Therapeutics, lnc. Patent 
Pending relating to PCT Publ. No. WO/201"L/L43669, and any related U.S. and foreign patents 
and patent applications.