B7-H2 (CD275, ICOSL), Fc fusion (Human) HiP™

Catalog #: 71130
Size: 100 µg
$310
Species: Human
Host Species: HEK293
MW: 53.3 kDa
Genbank #: NM_001283050
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 19-258
Description:

Human secreted B7 homolog 2 (B7-H2)-Fc fusion protein, also known as CD275, ICOSL, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050, a.a 19-258 fused to human IgG1 Fc region (a.a. 100-330) and expressed in a HEK293 cell expression system. MW = 53.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
O75144
Synonym(s):
B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP)
Formulation:
40 mM Tris-HCl, pH 8.0. 110 mM NaCl, 2.2 mM KCl and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at -80°C
Application(s):
Useful for the study ofprotein binding interactions, screening inhibitors, and selectivity profiling.
Reference(s):

1. Guillonneau, C., et al., Transplantation. 2005; 80(4): 546-554.
2. Fan, X., et al., J. Exp. Med. 2014; 211(4): 715-725.

Notes:
HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.
Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
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Product Datasheets

71130_Lot140603-D.pdf