Anti-CD27 Agonist Antibody

Catalog #: 100111-1
Size: 50 µg
$325
Catalog #: 100111-2
Size: 100 µg
$445
Species: Human
Host Species: HEK293
MW: Heavy Chain: 51 kDa; Light Chain: 27 kDa
Isotype: Human IgG1
Description:
Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.
Synonym(s):
Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, T14
Formulation:
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Purification:
Protein A affinity chromatography from HEK293 supernatants.
Format:
Aqueous buffer solution.
Storage / Stability:
Stable for at least 12 months at -80°C.
Application(s):
This antibody crosslinked with FcGR2B is useful for activation of CD27 costimulatory pathway in T cells.
Reference(s):

1. Vitale, L., et al., Clin Cancer Res. 2012; 18(14): 3812-3821. 

Warning(s):

Protect from light. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.

Scientific Category:
Immunotherapy
Product Type:
Antibody
Data shown is lot-specific. Contact us for specific information on other lots.

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$325

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Product Datasheets

100111_Lot180619.pdf