Anti-CD137 Agonist Antibody

Catalog #: 79097-1
Size: 50 μg
$325
Species: Human
Host Species: HEK293
MW: Heavy Chain: 52 kDa Light Chain: 26 kDa
Clonality: Monoclonal
Isotype: IgG1
Description:
Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.
Synonym(s):
Antibody, Anti CD137, Anti-CD137
Formulation:
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Purification:
Protein A affinity chromatography from HEK293 supernatants.
Application(s):
CD137 agonist antibody prevents tumor recurrence and metastases in cancer patients. This antibody is useful for activation of CD137 costimulatory pathway in T cells.
Reference(s):

1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.
2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Immunotherapy
Product Type:
Antibody
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Product Datasheets

79097-1.pdf