Anti-IL-17A Neutralizing Antibody

Catalog #: 91015
Size: 100 μg
$445
Species: Human
Host Species: HEK293
MW: 50 and 25 kDa for the heavy and light chains, respectively (150 kDa).
Clonality: Monoclonal
Isotype: IgG1k
Description:
Neutralizing recombinant human chimeric antibody recognizing human IL-17A. This antibody has not been tested for crossreactivity with other species.
Synonym(s):
IL-17, IL17, Interleukin-17A, CTLA8, Cytotoxic T-Lymphocyte-Associated Antigen 8
Assay Conditions:
Antibody was added at various concentrations using the IL- 17RA[Biotin]:IL-17A Inhibitor Screening binding assay (BPS Cat. #72060). Assay was performed according to the recommended protocol.
Formulation:
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Purification:
Purified using protein A affinity chromatography from HEK293 supernatants.
Format:
Aqueous buffer solution
Storage / Stability:
Stable for at least 12 months at -80°C.
Application(s):
Useful for binding studies and for the inhibition of IL-17RA:IL-17A interactions.
Reference(s):

1. Lubberts, E., et al., Arthritis Rheum. 2004; 50(2): 650-659.
2. Cheng, X., et al., Atherosclerosis. 2011; 215(2): 471-474.

Warning(s):
Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.
Scientific Category:
Immunotherapy
Product Type:
Antibody
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91015_Lot151110.pdf