ICOSL-CHO Recombinant Cell Line
Catalog #
79635
$6,500
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Purchase
Description
Recombinant CHO-K1 cells constitutively expressing human ICOSL (also known as human secreted B7 homolog 2 (B7-H2), CD275, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050.
Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
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Synonyms
B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP), B7-H2
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Product Data Gallery
Product Info
Storage and Usage
Citations
Host Cell Line
CHO, Chinese Hamster Ovary
Supplied As
Each vial contains ~ 2 x 10^6 cells in 1 ml of 10% DMSO.
UniProt #
O75144
Mycoplasma Testing
This cell line has been screened using the MycoAlert™ Mycoplasma Detection Kit (Lonza, #LT07-118) to confirm the absence of Mycoplasma contamination.
Background
ICOSL is the Ligand for the T-cell-specific cell surface receptor ICOS. When engaged by the ICOSL, the ICOS initiates a costimulatory signal for T-cell proliferation and cytokine production. It also induces B-cell proliferation and differentiation into plasma cells. The ICOS/ICOSL is a major regulator of the adaptive immune responses and also plays an important role in mediating local tissue responses to inflammatory conditions.