HSP90β (C-terminal), Biotin-labeled, His-tag, Avi-tag

Catalog #: 50313
Size: 100 µg
$460
Species: human
Host Species: E. coli
MW: 25 kDa
Genbank #: NM_001271969
Tag(s): N-terminal His-tag, N-terminal Avi-tag™
a.a: 527-724 (end)
Description:
Human Heat Shock Protein 90 beta (HSP90β), GenBank Accession No. NM_001271969, a.a. 527-724 (end) with N-terminal His-tag and N-terminal Avi-tag™, MW = 25 kDa, expressed in an E. coli expression system and enzymatically biotin-labeled using Avi-tag™ technology.
UniProt
P08238
Synonym(s):
Hsp90beta, heat shock protein 90 beta
Assay Conditions:
HSP90β (C-terminal):PPID binding activity measured using HSP90β (C-terminal) Inhibitor Screening Assay Kit, BPS Bioscience, Catalog # 50314.
Formulation:
40 mM Tris-HCl pH 8, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Milicevic, Z. et al., Int. J. Oncol. 2008 Jun;32(6):1169-78.
2. Chao, C.C. et al., J. Cell Biochem. 2008 Jul 1;104(4):1286-96.

Application Reference(s):
1. Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors (2017)

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Heat Shock Proteins
Product Type:
Recombinant Protein
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Product Datasheets

50313_Lot130607-G.pdf